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4 New Medicine in 2018 for Kidney Disease, Which Can Help You Keep Uremia Away

4 New Medicine in 2018 for Kidney Disease, Which Can Help You Keep Uremia Away
Here are 4 new medicines for kidney disease, which can help you keep uremia away.

1. Tolvaptan: to relieve PKD

Polycystic kidney disease (PKD) is the fourth leading cause of uremia. It is difficult to fundamentally solve polycystic kidney because of its genetic control.

Common symptoms of PKD include hypertension, pain, urinary tract infection, kidney stones, and so on. And treatment for PKD is mainly to control these symptoms.

In April 2018, the U.S. food and drug administration approved a new polycystic kidney drug: tolvaptan. It is used to treat adult acute progressive PKD so as to slow down the process of renal failure.

Contraindication: No urine, uremia, liver disease.

Note: due to its diuretic effect, it is necessary to replenish water to avoid dehydration.

2. Sodium zirconium cyclosilicate: to reduce blood potassium level

Potassium is closely related to heart function, so high blood potassium is also linked to a risk of death. Hyperkalemia is a common complication in renal failure patients, with an incidence of 10% to 32%, which can induce arrhythmia.

Sodium zirconium cyclosilicate was approved by the European commission in March 2018.

It is an oral potassium binding agent that can quickly restore blood potassium to normal and effectively reduce levels of blood potassium in patients with chronic kidney disease, heart failure, diabetes, and ACEI or ARBs treatment.

Indication: hyperkalemia (non-emergency treatment).

Contraindications: severe constipation, ileus, or impaction, including postoperative gastrointestinal motility.

Note:  do not take the medicine together with other drugs, 2 hours before and after

3. Zemdri: anti-infection

People with kidney disease usually have low immunity and are susceptible to infection. Female patients are often plagued by urinary tract infections, which can lead to pyelonephritis when the bacteria enters the renal pelvis.

Zemdri, a new class of aminoglycoside antibiotics, was approved in June 2018 to treat urinary tract infections caused by e.coli, klebsiella pneumoniae, proteobacteria, and enterobacter cloacae, including pyelonephritis.

Most of the existing aminoglycoside antibiotics are less effective because of resistance, but Zemdri can avoid resistance.

4. Prolia: to treat osteoporosis

You run a risk of osteoporosis from the fifth month of usage of Glucocorticoid (such as cortisone, prednisone, dexamethasone, etc.). It can cause fracture, femoral head necrosis, but steroids are often taken for a year or more, or even for a lifetime.

Prolia was approved in May 2018 for hormone-induced osteoporosis, which can increase bone density in men and women at high risk of fractures. Subcutaneous injections every six months.

Now you know the 4 new medicines for kidney disease. Let’s look forward to more new medicine to be produced.

Tag: CKD CKD Treatment
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