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It’s Not Dialysis that Often Takes the Lives of People with CKD, but....

It’s Not Dialysis that Often Takes the Lives of People with CKD, but....
Recently many CKD patients left messages and asked: Doctor, my kidneys does not work well. Why is statin medicine that reduces blood lipids prescribed?

In fact, before progressing to the uremia stage, most patients with CKD will die from the cardiovascular complications (heart failure and stroke are the main factors), and for dialysis patients, half of them die from cardiovascular disease, and their incidence is 10 times higher than the general population. So it's often not dialysis that takes away the lives of people with chronic kidney disease, but cardiovascular disease. Therefore, prevention of cardiovascular disease is the key to improve the prognosis of patients with CKD.

Hyperlipidemia, hypertension, diabetes, proteinuria... All of them are risk factors for cardiovascular diseases in patients with CKD.

After hyperlipidemia damages blood vessels and endothelial cells, it causes tissue inflammation and accelerates the process of kidney disease. Only by actively controlling hyperlipidemia can we reduce the risk of cardiovascular disease in patients with CKD and slow down the progression of kidney disease.

Statins are in a core position in the treatment of dyslipidemia in chronic kidney disease (CKD). Improving the Prognosis of Global Kidney Disease Organization recommends that all CKD patients over 50 years old should be treated with statins. For patients with long-term dialysis, if statins or the combination of statin and Ezetimibe have been started, they should keep on treatment after dialysis. In other cases, it is unnecessary. For CKD patients aged 18-49 years old who do not receive long-term dialysis, if they are diagnosed with ischemic stroke, coronary heart disease or diabetes, they can also take statins.

For patients with CKD, long-term lipid lowering should be done based on statin according to their lipid metabolism under the guidance of doctors so as to reduce the risk of cardiovascular disease and delay the progression of kidney disease.

Although statin plays an important role in the treatment of cardiovascular diseases in patients with CKD, it also has side effects mainly including muscle injury and liver injury.

Therefore, patients with CKD should be tested for liver enzymes before and after treatment with statin, and liver function should be reviewed once every 1 to 2 months, and then the review cycle can be slowly adjusted to 6 to 12 months.

If the liver enzyme elevates, continue to take or suspend the administration of the drug according to the degree of elevation, and review the liver function on time until normal.

Patients with CKD have different renal function, and the type and dose of statin will be different, so you should take it according to the doctor's advice.

Tag: CKD CKD Symptoms
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